Year: 2018 I Volume: 2 I Issue: 1 I Page:

Capecitabine Induced Hand-Foot Syndrome

1 Senior resident, Department of Dermatology, Venereology and Leprosy, SMS Medical College, Jaipur.

Corresponding Author:
Dr. Astha Sharma
B1/92, Chitrakoot Yojna
Jaipur-302021, Rajasthan


Hand foot syndrome (HFS), also called palmar-plantar erythrodysaesthesia, is a cutaneous toxic reaction to several chemotherapeutic drugs. Most commonly implicated drugs are cytarabine, doxorubicin, capecitabine, epirubicin, docetaxel and 5-fluorouracil. Clinically it is characterized by dysesthesia, erythema, edema, and desquamation of palms and soles. We report a 52 year old patient of hand-foot syndrome on treatment with capecitabine for colorectal cancer.

Key words: Capecitabine, Hand and Foot Syndrome, Palmar-Plantar Erythrodysaesthesia